Selective Involvement of Serum Response Factor in Pressure-Induced Myogenic Tone in Resistance Arteries
نویسندگان
چکیده
منابع مشابه
Selective involvement of serum response factor in pressure-induced myogenic tone in resistance arteries.
OBJECTIVE In resistance arteries, diameter adjustment in response to pressure changes depends on the vascular cytoskeleton integrity. Serum response factor (SRF) is a dispensable transcription factor for cellular growth, but its role remains unknown in resistance arteries. We hypothesized that SRF is required for appropriate microvascular contraction. METHODS AND RESULTS We used mice in which...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2013
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.112.300708